Deciphering the Electrophysiological Mechanisms for Ibrutinib-Induced Ventricular Arrhythmias
نویسندگان
چکیده
منابع مشابه
Ventricular arrhythmias and electrophysiological consequences of myocardial ischemia and infarction.
The derangements of cardiac rhythm that result from occlusion of coronary arteries caught the attention of the earliest experimenters in the field. By the time of the studies of Porter in 1894, it was known that "fibrillar contractions" often were the end result of coronary occlusion and that irregularities of cardiac rhythm commonly preceded terminal ventricular fibrillation. Porter remarked t...
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OBJECTIVES This study sought to compare and contrast the clinical and electrophysiological characteristics of outflow tract arrhythmias. BACKGROUND Idiopathic ventricular outflow tract arrhythmias manifest clinically in 3 forms: 1) paroxysmal sustained monomorphic ventricular tachycardia (SMVT), 2) repetitive nonsustained ventricular tachycardia (NSVT), or 3) premature ventricular contraction...
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OBJECTIVE To explore the cardiac electrophysiological characteristics of cardiac hypertrophy and its influence on the occurrence of ventricular tachyarrhythmias. METHODS Adult C57BL6 mice were randomly divided into a surgery group and a control group. Thoracic aortic constriction was performed on mice in the surgery group, and cardiac anatomical and ultrasonic evaluations were performed to co...
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Ventricular fibrillation (VF) is known as a main responsible cause of sudden cardiac death which claims thousands of lives each year. Although the mechanism of VF induction has been investigated for over a century, its definite mechanism is still unclear. In the past few decades, the development of new advance technologies has helped investigators to understand how the strong stimulus or the sh...
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Our goal was to better understand the mechanisms underlying muscarinic receptor actions on the ventricle in vivo. Therefore, we studied the effects of vagal stimulation on ventricular repolarization and of vagal tone on lethal arrhythmias induced by 30 minutes of left anterior descending coronary artery ligation in anesthetized cats. Experimental groups included normal control cats subjected on...
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ژورنال
عنوان ژورنال: JACC: CardioOncology
سال: 2020
ISSN: 2666-0873
DOI: 10.1016/j.jaccao.2020.10.001